PCI Ventures

PCI Ventures supports the creation of spinouts from Penn through targeted programs and activities

PCI Ventures (PCIV) is a division of PCI specifically focused on creating early-stage businesses founded on Penn technology.

PCIV prides itself on promoting entrepreneurial activities and new company formation around Penn’s leading research and innovations. PCIV actively seeks entrepreneurs to lead its companies and investors to provide funding for a portfolio of new ventures in development. PCIV also provides a suite of products and services to support its portfolio as spinouts make their way towards commercial success.

How PCIV Helps Penn Spinouts

Since 2010, PCIV has worked with over 200 faculty and staff members to form and launch new companies based on selected inventions and innovative technologies.

While there are many paths to commercialization of a new technology, the PCIV team works with Penn inventors to develop a commercial strategy that utilizes company creation as a means to increase the value of the technology while giving it exposure in the marketplace. PCIV will assist the business team through the entire commercialization process with an array of services that includes matching a strong entrepreneur to each company, providing a network of partners to help with any number of startup needs, and assisting with fundraising.

By connecting local entrepreneurs, investors and partners with Penn inventors, PCIV adds a powerful platform for a larger entrepreneurial ecosystem in greater Philadelphia and beyond.

PCI Ventures Services

UPstart

UPstart offers a wide array of services to assist entrepreneurial faculty members with the company formation and development process. UPstart smooths the path to future success by working closely with faculty members to create a commercial opportunity for their technology through a new venture.

UPadvisors

UPadvisors provides support to companies that operate independently and want to leverage the resources of the PCI Ventures team, services, programs, and network to help navigate the challenges of an early-stage startup. PCI Ventures provides a Company Formation Handbook and advises UPadvisors companies during Weekly Office Hours.

Venture WarmUP

Venture WarmUP is designed to assist faculty prior to starting a company as they explore different options for technology development and commercialization. Program participants may choose to work with PCI to pursue licensing or R&D alliance opportunities, start a company through PCI Ventures, start a company on their own (or with an outside partner), or simply continue with additional research.

PCI Ventures Weekly Office Hours

PCI Ventures  hosts virtual office hours several times a semester. During the office hour sessions, a member of the PCI Ventures team will be available to answer business questions on topics ranging from company formation and legal agreements to benefits and insurance.

Anyone is welcome to take advantage of the office hours. Sign up for a virtual session using the links below:

Our Portfolio

Read about the wide variety of companies in the PCIV portfolio here.

View Our Full Portfolio

Vetigenics

Vetigenics

Using novel phage-display techniques to develop reagents and therapeutics for veterinary medicine

Penn Founder: Nicola Mason, BVetMed, PhD (Penn Veterinary Medicine)

PCI Ventures (UPstart)

Innervace

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Innervace

Implantable tissue engineered brain pathways for neurodegenerative disorders.

Penn Founder: D. Kacy Cullen, PhD (Penn Medicine)

PCI Ventures (UPadvisors)

FluidiSpec

FluidiSpec

Developing microfluidic systems for proteomic analysis of small samples for research tools and clinical analyses.

Penn Founder: Aaron Timperman, PhD, and Lumala Nelum Perera, PhD (Penn Engineering)

PCI Ventures (UPadvisors)

Advac Therapeutics

Advac Therapeutics

Development of vaccines and therapeutics for the treatment of infectious diseases and cancers

Penn Founder: Hao Shen, PhD (Penn Medicine)

PCI Ventures (UPadvisors)

SpaxaBio

SpaxaBio

Uses AI to connect molecules and morphology, building intelligent tissue maps that power the future of precision medicine.

Penn Founders: Mingyao Li, Ph.D (Biostatistics and Epidemiology)

PCI Ventures (UPstart)

Onocor

Onocor

Catheter based retrieval systems designed to recovered malposition cardiovascular devices

Penn Founders: Joseph Gorman, MD, Robert Gorman, MD & Matthew Gillespie, MD (Penn Medicine)

PCI Ventures (UPstart)

Upcoming Events

All Events

PCI Ventures Office Hours with Yi-Yen Chen (Virtual)

June 24 @ 9:00 am

More Info

PCI Open Office Hours at Penn Engineering

June 24 @ 11:00 am

More Info

Apply to the 2026 Philadelphia Regional Startup World Cup Pitch Competition

July 15 @ 12:00 am

More Info

Our Partners

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